New strain multidrug resistant tuberculosis G24767 in Puerto Rico: Old disease a continuous threat
نویسندگان
چکیده
Multidrug resistant tuberculosis (MDR-TB) is defined as a Mycobacterium tuberculosis strain resistant to two or more first-line anti-tuberculous drugs. Tuberculosis (TB) is a global threat to society despite improvement in therapy as it continues to be an economic burden especially in underdeveloped countries. The downfall of global economics and growing travel destinations in developing countries has escalade the exposure of organism not previously encountered in industrialized nations. Most cases of MDR-TB are reported on immunosuppressed patients with risk factors and from endemic areas. Nevertheless new strains with higher transmission degree are emerging as a threat in patients who have low risk factors for the development of MDR-TB.
منابع مشابه
Molecular Epidemiology of Multidrug-Resistant Tuberculosis, New York City, 1995–1997
From January 1, 1995, to December 31, 1997, we reviewed records of all New York City patients who had multidrug-resistant tuberculosis (MDRTB); we performed insertion sequence (IS) 6110-based DNA genotyping on the isolates. Secondary genotyping was performed for low IS6110 copy band strains. Patients with identical DNA pattern strains were considered clustered. From 1995 through 1997, MDRTB was...
متن کاملExtensively drug-resistant (XDR) tuberculosis: an old and new threat.
Tuberculosis (TB) remains a worldwide emergency (8 million new cases per year, 2 million deaths annually) mostly affecting poor countries. To this old, persistent threat, a new emergency is adding further challenge, i.e., the multidrug-resistant TB, which in its extreme and highly lethal form is called XDR TB (extensively drug-resistant TB). How to fight XDR TB is a high research and public hea...
متن کاملDisseminated multiorgan MDR-TB resistant to virtually all first-line drugs.
The emergence of multidrug-resistant tuberculosis (MDR-TB) is a major global concern since, despite a complex treatment regime, it still remains a lethal threat. A 21-yr-old male HIV-negative migrant from Burma presented with a disseminated tuberculosis affecting the lung, spleen, liver, mediastinal and abdominal lymph nodes. This particular strain of Mycobacterium tuberculosis proved to be res...
متن کاملAcquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis.
Treatment of multidrug-resistant Mycobacterium tuberculosis is a challenge. This letter describes the emergence of resistance to new therapies, bedaquiline and delamanid.
متن کاملDraft Genome Sequence of Klebsiella pneumoniae Carbapenemase-Producing Acinetobacter baumannii Strain M3AC9-7, Isolated from Puerto Rico
We report the draft genome of a multidrug resistant, Klebsiella pneumoniae carbapenemase (KPC)-producing Acinetobacter baumannii strain M3AC9-7 that belongs to the novel sequence type, ST250. The draft genome consists of a total length of 4.09 Mbp and a G+C content of 38.95%.
متن کامل